Stage 1: The tumor is found in the pleura with or without some involvement of the lung, pericardium (lining of the heart) or diaphragm.
Stage 2: The tumor is found in a stage I location, plus there is involvement of some lymph nodes in the chest.
Stage 3: The tumor has extended into the chest wall, ribs or heart, through the diaphragm or into the peritoneum (the abdominal lining). There also may be involvement of the lymph nodes.
Stage 4: The tumor has spread through the bloodstream to distant sites (it has metastasized).
The Brigham staging system
This is based on whether the mesothelioma can be removed by surgery and whether the lymph nodes are involved or not. Again there are four stages, which are similar to the TNM system.Stage 1: mesothelioma can be removed with surgery and there are no lymph nodes containing cancer cells
Stage 2: mesothelioma can be removed with surgery but there are lymph nodes containing cancer cells
Stage 3: mesothelioma cannot be removed with surgery because it has spread into the chest wall, heart, or through the diaphragm into the peritoneum. There may or may not be lymph nodes containing cancer cells
Stage 4: mesothelioma has spread via the bloodstream to other organs in the body such as the liver, brain or bone
Peritoneal mesothelioma stages
There is no established staging system for peritoneal mesothelioma. If your cancer is staged it may be done according to the TNM system. The TNM system is the staging system most commonly used in cancer. The TNM system describes the extent of the primary tumour (T), the absence or presence of cancer in nearby lymph nodes (N), and the absence or presence of distant metastases (M).